Lipid Nanoparticles Market Set to Reach USD 2,886.07 Million by 2032, Driven by mRNA Technology and Drug Delivery Innovation – SNS Insider
SNS Insider Unveils Strategic Insights into the U.S. Lipid Nanoparticles Market’s Rapid Growth—Valued at USD 333.94 Million in 2023—As the U.S. Leads More Than 38% of Global Share Amid Explosive Demand for RNA Therapeutics and Advanced Drug Deliver
Austin, June 10, 2025 (GLOBE NEWSWIRE) — According to SNS Insider, the global Lipid Nanoparticles Market was valued at USD 878.9 million in 2023 and is anticipated to reach USD 2,886.07 million by 2032, growing at a CAGR of 14.15% during the forecast period 2024–2032.
The market size of U.S. Lipid Nanoparticles was significantly large in the year 2023, which was USD 333.94 Million, and is expected to go up to USD 1043.14 Million by 2032. This has been driven by a robust biopharmaceutical R&D landscape and regulatory backing, as well as the adoption of innovative delivery platforms in drugs and vaccines.
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Market Overview
Lipid nanoparticles have revolutionized drug delivery as they improve the bioavailability and stability of therapeutic molecules, including nucleic acid-based drugs. Most recently, their contribution was central in the successful implementation of RNA-based vaccines against COVID-19, which gave an unprecedented boost as the funding and research on these lines were accelerated at a high pace. As investment in nanomedicine and clinical advancements of mRNA-based therapies continues to rise, the LNP technology is fast becoming a keystone of modern drug delivery systems.
In the U.S., a strong infrastructure in biotechnology, growing FDA approvals for formulations of nanoparticles, and excellent cooperation between the pharma heavyweights and the new biotech companies drive market growth. Additionally, public and private investments in precision medicine and RNA therapeutics are also fueling the uptake of lipid nanoparticles in commercial and clinical activities.
Major Players Analysis Listed in this Report are:
- Ionis Pharmaceuticals (Vyondys 53, Waylivra)
- CureVac (CVnCoV, CureVac’s mRNA vaccines)
- Alnylam Pharmaceuticals (Onpattro, Givlaari)
- Moderna (mRNA-1273 (Spikevax), mRNA-1010)
- Arcturus Therapeutics (ARCT-810, LUNAR-COV19)
- VivoCapital (VLP-based vaccines, Lipid nanoparticle formulations for RNA delivery)
- Novartis (Kymriah, Leqvio)
- Pfizer (Comirnaty, BNT162b2)
- Bayer (Vitrakvi, Kovaltry)
- Sanofi (mRNA vaccine candidates, Dupixent)
- Sangamo Therapeutics (SB-525, Zinc Finger Nucleases)
- Horizon Therapeutics (Tepezza, Ravicti)
- Genevant Sciences (GENE-012, GENE-001)
- Enzyvant (VY-AADC, VY-GLB1)
- Dicerna Pharmaceuticals (DCR-PHXC, DCR-HBVS)
- Takeda Pharmaceuticals (TAK-999, Velcade)
- Silence Therapeutics (SLN124, SLN360)
- Revelo Genetics (RNA-based diagnostics, RNA-based therapeutics)
- Dynavax Technologies (HEPLISAV-B, CpG 1018)
- Translate Bio (mRNA-based therapies, TB-403)
Lipid Nanoparticles Market Report Scope
| Report Attributes | Details |
| Market Size in 2023 | US$ 878.9 million |
| Market Size by 2032 | US$ 2886.07 million |
| CAGR | CAGR of 14.15% From 2024 to 2032 |
| Base Year | 2023 |
| Forecast Period | 2024-2032 |
| Historical Data | 2020-2022 |
| Regional Analysis | North America (US, Canada, Mexico), Europe (Germany, France, UK, Italy, Spain, Poland, Turkey, Rest of Europe), Asia Pacific (China, India, Japan, South Korea, Singapore, Australia, Rest of Asia Pacific), Middle East & Africa (UAE, Saudi Arabia, Qatar, South Africa, Rest of Middle East & Africa), Latin America (Brazil, Argentina, Rest of Latin America) |
Segment Analysis
By Product:
Ionizable lipids became the most desired product type in 2023 due to their importance in nucleic acid delivery. These lipids have the special ability to change charge at various pHs, which facilitates efficient encapsulation and release of genetic materials in the cells being targeted. Product (Ionizable Lipid, Nucleic Acid) Ionizable lipid held the major share in the product segment due to its utilization in leading mRNA vaccine formulations and current clinical progressions.
By LNP Type:
The Solid Lipid Nanoparticles (SLNs) segment held a majority of the market share, accounting for 42% in the year 2023. Due to their stability, controlled drug release properties, and the possibility of upscaling production, SLNs are increasingly used in both pharmaceutical and cosmetic fields. Further, Nanostructured Lipid Carriers (NLCs) are emerging as the most promising segment. Most appealing, NLCs present high drug loading and improved release profiles and are very suitable vehicles for hydrophilic and lipophilic drugs.
By Application:
Based on end-use industry, the market is dominated by Commercial applications and accounted for 52% of the market share in 2023. This can be attributed mainly to the commercialization of lipid nanoparticle-based vaccines and medicines. The clinical application segment is also experiencing growth due to the rising number of clinical trials and the emerging RNA-based therapies for rare diseases, oncology, and metabolic disorders.
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Lipid Nanoparticles Market Segmentation
By Product
- Ionizable lipids
- PEGylated lipids
- Neutral lipids
- Phospholipids
- Other Formulation Materials
By LNP Type
- Solid lipid Nanoparticles (SLNs)
- Nanostructured lipid Carriers (NLCs)
- Other Types
By Molecule Type
- siRNA
- mRNA
- Other Molecules
By Application
- Commercial
- Clinical
By End User
- Pharmaceutical & Biotechnology Companies
- Academic & Research Institutes
- CDMO’s
By Service Type
- Formulation Development Services
- Manufacturing Services
- Other Services
Regional Analysis
North America dominated the global lipid nanoparticles market in 2023. The dominance of North America in this market is mainly attributed to its strong biotech industry, regulatory approvals, and the adoption of mRNA technology. The US continues to be the epicenter for the development and commercialization of lipid nanoparticle platforms.
The fastest growth is expected to be in the Asia-Pacific region, where pharmaceutical outsourcing growth, increasing R&D investments, and the growing biopharma sector, especially in China, India, and South Korea, could drive the demand. Moreover, growing government support and global partnerships are facilitating the growth of the regional market.
Recent Developments
- January 2024 – Genevant Sciences launched a new LNP platform for extrahepatic delivery of mRNA-based therapies.
- March 2024 – Precision NanoSystems, a subsidiary of Cytiva, introduced a next-gen LNP formulation kit to streamline preclinical development of mRNA vaccines.
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Table of Contents – Major Key Points
1. Introduction
2. Executive Summary
3. Research Methodology
4. Market Dynamics Impact Analysis
5. Statistical Insights and Trends Reporting
6. Competitive Landscape
7. Lipid Nanoparticles Market by Product
8. Lipid Nanoparticles Market by LNP Type
9. Lipid Nanoparticles Market by Molecule Type
10. Lipid Nanoparticles Market by Application
11. Lipid Nanoparticles Market by End User
12. Lipid Nanoparticles Market by Service Type
13. Regional Analysis
14. Company Profiles
15. Use Cases and Best Practices
16. Conclusion
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