New research: One vaccine dose enough for five people

As people are now fleeting to get vaccines, there is a severe shortage of COVID-19 vaccines. Other than mass production of vaccines there is another way to ramp up the vaccination program. Experts say this can be done by administering a smaller quantity of the vaccine in an intradermal (ID) way.

The intradermal way is done by injecting 0.1ml into the skin, which is one-fifth of the volume of the prevailing dose that is being administered, which is 0.5ml given intramuscularly in the shoulder. To break it down, one dose that was vaccinating 1 person can now vaccinate 5 people via the intradermal route.

The Technical Advisory Committee chairman Dr.MK Sudarshan has said that this method has been successful in the rabies vaccine in the past and that the concentration of antigen-processing cells in the skin is the reason for the “strong immunologic response to vaccines administered through the skin, despite the lower amount of vaccines injected.”

In addition to that, he also mentioned that the intradermal shot is anticipated to incite “precisely the regional lymph nodes and quickly generate an immune response” that can in certain situations be better than the intramuscular response that is in play with the current dose of vaccines. Dr.MK Sudarshan has previous experience and expertise from working on rabies vaccines.

 

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